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動(dòng)脈硬化閉塞癥和深靜脈血栓形成患者同型半胱氨酸臨床檢測(cè)結(jié)果及臨床意義

摘要:目的: 探討動(dòng)脈硬化閉塞癥(ASO)和靜脈血栓形成(VT)患者同型半胱氨酸(Hcy)變化。 方法 :通過循環(huán)酶法對(duì)34例非動(dòng)脈硬化閉塞癥(ASO)和靜脈血栓形成(VT)患者(對(duì)照組),30例動(dòng)脈硬化閉塞癥(ASO)患者和26例靜脈血栓形成(VT)患者血液中Hcy進(jìn)行測(cè)定。 結(jié)果 :循環(huán)酶法測(cè)定HCY的批內(nèi)平均變異系數(shù)為2．23％,批間平均變異系數(shù)為1．59％。34例對(duì)照組,〖WTBX〗t =1135,〖WTBX〗P =0266gt;005;動(dòng)脈硬化閉塞癥(ASO)組Hcy含量明顯高于對(duì)照組(〖WTBX〗P lt;O．05),靜脈血栓形成(VT)組Hcy含量高于對(duì)照組(〖WTBX〗P lt;0．O5)。 結(jié)論 :高同型半胱氨酸血癥可能是動(dòng)脈硬化閉塞癥(ASO)和靜脈血栓形成(VT)及復(fù)發(fā)的致病因素。可將同型半胱氨酸作為動(dòng)脈硬化閉塞癥(ASO)和靜脈血栓形成(VT)及復(fù)發(fā)的重要指標(biāo)。Abstract: Objective: TO syudy the changes of the Homocysteine about Atherosclerosis obliterans and Venous thrombosis patients. Methods : To measure the Hcy in the blood of 34 healthy cases both non ASO and non VT(the comparison group),30 cases of ASO patients and 26 cases of VT patients respectively by enzymatic cycling assay?！糤THZ〗Results :The average variation coefficient of Hcy within the groups was 223% and among the groups was 159% measured by enzymatic cycling assay.In the 34 cases of comparison group,t=1135,P=0266gt;005,The content of Hcy in the blood of ASO patients group were significantly higher than the comparision group (Plt;005),and the content of Hcy in the blood of VT patients group were also higher than the comparison group (Plt;005). Conclusion : Hyper Hcy may be the pathogenic diathesis to form or to recrudesce ASO and VT.So we can treat Hcy as the significant index to form or to recrudesce ASO and VT.