摘要:目的:探討血小板動(dòng)態(tài)變化與新生兒重癥肺炎之間的關(guān)系。方法:測(cè)定40例新生兒重癥肺炎患兒急性期(3天)及恢復(fù)期(10天)的血小板計(jì)數(shù)(platelet count, PLT)計(jì)數(shù)、平均血小板溶劑(mean platelet volume, MPV)、血小板壓積(platelet hematocrit, PCT)及血小板分布寬度(platelet distribution width, PDW),并進(jìn)行比較。結(jié)果:40例重癥肺炎患兒中,PLT隨病情好轉(zhuǎn)而上升,PCT、MPV、PDW水平隨病情好轉(zhuǎn)而下降。急性期PLT、PCT、MPV、PDW的水平與恢復(fù)期相比,差異有統(tǒng)計(jì)學(xué)意義(Plt;0.05)。結(jié)論:動(dòng)態(tài)的觀察血小板參數(shù)及其變化有助于新生兒重癥肺炎的評(píng)估及療效觀察。Abstract : Objective: To assess the relationship between neonatal severe pneumonia and platelet. Methods: We test platelet count, mean platelet volume, platelet hematocrit and platelet distribution width in 40 patients whom diagonosed neonatal svere pneumonia; moreover, we compared the platelet change in acute phase and recovery phase. Results: Mean platelet volume, platelet count increased with recovery of pneumonia (Plt;0.05). Conclusion: Observing platelet change is helpful for the evaluation of neonatal pneumonia.