• 四川大學(xué)華西醫(yī)院腎內(nèi)科,四川成都 610041;

目的:回顧性分析不同年齡組IgA腎病患者的病理改變特點,以利于早期診斷和治療。方法:將我院280例(2005~2007年)經(jīng)皮腎活檢確診為原發(fā)性IgA腎病的患者按不同年齡分為兒童組、青少年組和成人組,逐項分析病例組織光鏡和免疫熒光檢查的相關(guān)資料。結(jié)果:在280例病理資料中,兒童組患者病理學(xué)分級以Ⅰ~Ⅱ級為主,免疫熒光檢查以單純IgA 和或C3沉積多見;青少年組患者病理學(xué)分級以Ⅰ~Ⅲ級為主,免疫熒光檢查也是以單純IgA 和或C3 沉積多見;成人組病理學(xué)改變從Ⅰ~Ⅳ級均可見到,主要以Ⅲ ~Ⅳ級為主,免疫熒光檢查以單純IgA 、IgA + IgM和或C3沉積較多。結(jié)論:IgA腎病的病理改變有隨著年齡增大,病理改變越明顯腎臟損害越嚴(yán)重的趨勢,早期進行經(jīng)皮腎活檢有利于明確診斷及盡早治療。

引用本文: 馬云霞,馬行一,米緒華,胡章學(xué),欒森. 280例IgA腎病患者不同年齡組病理分析. 華西醫(yī)學(xué), 2009, 24(2): 310-312. doi: 復(fù)制

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  5. 5. Li LS,Liu ZH.Epidemiologic data of renal diseases from a single unit in China:analysis based on 13,519 renal biopsies[J].Kideny Int,2004,66:920-923..
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