目的 探討影響巖斜區(qū)腦膜瘤(PCM)預(yù)后的相關(guān)因素。 方法 回顧分析解放軍452醫(yī)院2005年9月-2009年6月及四川大學(xué)華西醫(yī)院1999年9月-2009年2月110例患者的臨床資料及隨訪結(jié)果,通過單因素生存分析及Cox比例風(fēng)險模型分析探討影響PCM預(yù)后的相關(guān)因素。 結(jié)果 單因素生存分析發(fā)現(xiàn)8種相關(guān)因素影響PCM患者的預(yù)后,但Cox多因素分析僅發(fā)現(xiàn)腦干T2像高信號(OR=5.54,P=0.012)、腫瘤侵入腦干(OR=5.10,P=0.034)、病理高級別(OR=4.03,P=0.011)這3種因素有統(tǒng)計學(xué)意義。 結(jié)論 腦干T2像高信號、腫瘤侵入腦干、病理高級別可影響巖斜區(qū)腦膜瘤患者的預(yù)后。
引用本文: 魏攀,張躍康,莊進(jìn)學(xué),陳登奎,陶傳元,薛峰,張煒,李海龍,鄭小強(qiáng). 巖斜區(qū)腦膜瘤術(shù)后預(yù)后相關(guān)因素分析. 華西醫(yī)學(xué), 2012, 27(7): 997-1000. doi: 復(fù)制
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- 1. 余新光.巖斜區(qū)腫瘤手術(shù)人路選擇及相關(guān)問題[J].中華神經(jīng)外科雜志, 2005, 21(3): 321-322.
- 2. Galindo GM , Sanz OJ. Vascular enueration as a prognsticator for colorectal carcinoma[J]. Eur J Cancer, 2000, 36(1): 55-60.
- 3. Teo P , Lee WY. Significant prognosticators after primary radiot herapy in 903 nodisseminated nasopharyngeal carcinoma evaluated by computer tomography[J]. Oncol Biol Phys, 1996, 36(2): 291-304.
- 4. Shafqat S, Elkind, M, Chiocca EA, et al. Petroclival meningioma presenting with pathological laughter[J]. Neurology, 1998, 50(7): 1918-1919.
- 5. Carvalho GA, Matthies C, Tatagiba M, et al. Impact of computed tomographie and magnetic resonance imaging findings On surgical outcome in petroclival meningiomas[J]. Neurosurgery, 2000, 47(6):1287-1294..
- 6. Samii M. Experience with 36 cases of petroclival meningiomas[J].Acta Neurochir (Wien), 1992, 118(4): 27-32.
- 7. Sekhar LN, Jannetta PJ, Burkhart LE, et al. Meningiomas involving the clivus : a six-year experience with 41 patient[J]. Neurosurgery, 1990, 27(6): 764-781.
- 8. Sekhar L, Swamy NKS, Jaiswal V, et al. Surgical excision of meningiomas involving the clivus: preoperative and intraoperative features as predictors of postoperative functional deterioration[J]. Neurosurg, 1994, 81(2): 860-868.
- 9. 蘇健光, 李士其, 汪寅. 非典型腦膜瘤預(yù)后分析[J]. 中國臨床神經(jīng)外科雜志, 2007, 12(3): 196-198.
- 10. Joseph E, Sandhyamani S, Rao MB, et al. Atypical meningioma:a clinicopathological analysis[J]. Neural India, 2000, 48(4): 338-342.
- 11. Jaakskelainen J, Haltia M, Servo A. Atypical and anaplastic meningiomas: radiology, surgery, radiotherapy and outcome [J]. Surg Neurol, 1986, 25(5): 233-242.
- 12. Ryojo AG, Mario NL, Laligam N. Patient-evaluated outcome after surgery for basal meningiomas[J], Neurosurgery, 2002, 50(3): 941-949.
- 13. Bateman BT, Spellman J P, Gutin PH, et al. Meningioma resectionin the elderly: nationwide inpatient sample [J]. Neurosurgery, 2005, 57(5) : 855.
- 14. Sabareesh K, Natarajan, Laligam N, et al. Petroclival meningiomas: multimodality treatment and outcomes at long-term follow-up[J]. Neurosurgery, 2007, 60(6): 965-981.
- 15. Sonodal Y, Sakuradal K, Sainol M, et al. Multimodal strategy formanaging menigiomas in the elderly[J]. Acta Neurochirurgica, 2005, 147(2): 131.