目的 提高對肺上皮樣血管內(nèi)皮細(xì)胞瘤臨床診治的認(rèn)識。方法 報告1 例肺上皮樣血管內(nèi)皮細(xì)胞瘤病例并進(jìn)行相關(guān)文獻(xiàn)復(fù)習(xí)。結(jié)果 患者為29 歲男性, 反復(fù)咳嗽10 個月。多次胸部CT均顯示雙肺多發(fā)性結(jié)節(jié)影, 臨床診斷為肺癌、結(jié)節(jié)病、結(jié)核。最后經(jīng)胸腔鏡開胸肺活檢病理診斷為肺上皮樣血管內(nèi)皮細(xì)胞瘤。結(jié)合本例并復(fù)習(xí)近20 年國內(nèi)外文獻(xiàn)報道的110 例肺上皮樣血管內(nèi)皮細(xì)胞瘤( 國外96 例, 國內(nèi)14 例) 資料。結(jié)果顯示本病女性多見, 發(fā)病年齡7 ～83 歲; 咳嗽為常見癥狀, 胸部CT 表現(xiàn)為結(jié)節(jié)影。確診主要依靠手術(shù)病理檢查。目前尚無有效的治療措施。結(jié)論 肺上皮樣血管內(nèi)皮細(xì)胞瘤是一種罕見病, 臨床無特異性, 極易誤診。
引用本文： 王玉珠,金洪,姜勇. 肺上皮樣血管內(nèi)皮細(xì)胞瘤一例并文獻(xiàn)復(fù)習(xí). 中國呼吸與危重監(jiān)護(hù)雜志, 2010, 9(6): 641-643. doi: 復(fù)制
| 1. | Dail DH, Liebow AA, Gmelich JT, et al, Intravascular, bronchiolar,and alveolar tumor of the lung( IVBAT) . An analysis of twenty cases of a peculiar sclerosing endothelial tumor. Cancer, 1983, 51 : 452 -464. |
| 2. | Amin RM, Hiroshima K, Kokubo T, et al. Risk factors and independent predictors of survival in patients with pulmonary epithelioid hemangioendothelioma. Review of the literature and a case report. Respirology, 2006, 11: 818 -815. |
| 3. | 葉甫登, 張峰. 肺上皮樣血管內(nèi)皮瘤( 附1 例報告及文獻(xiàn)復(fù)習(xí)) .臨床肺科雜志, 2007, 12: 332-334 . |
| 4. | Weiss SW, Ishak KG, Dail DH, et al. Epithelioid hemangioendothelioma and related lesions. Semin Diagn Pathol,1986, 3: 259 -287. |
| 5. | Schattenberg T, Kam R, Klopp M, et al. Pulmonary epithelioid hemangioendothelioma: report of three cases. Surg Today, 2008, 38 :844-849. |
| 6. | Bharadwaj R, Hejmadi R, Desai S. Pericardial effusion and raised CA-125 level-unusual manifestations of primary pulmonary epithelioid hemangioendothelioma. Indian J Cancer, 1999, 36: 194 -197. |
| 7. | Travis WD, Brambilla E, Mueller-Hermelink HK, et al. Pathology and genetics of tumours of the lung, pleure, thymus and heart. WHO classification of tumours. Lyon: IARC Press; 2004 . |
| 8. | Fagen K, Silverman ED, Cole RL. et al. Detection of a pulmonary epithelioid hemangioendothelioma by FDG PET Scan. Clin NuclMed, 2004, 29: 758-759 . |
| 9. | Cronin P, Arenberg D. Pulmonary epithelioid hemangioendothelioma:an unusual case and a review of the literature. Chest, 2004, 125:789-793. |
| 10. | Ross GJ, Violi L, Friedman AC, et al. Intravascular bronchioloalveolar tumor: CT and pathologic correlation. J Comp Assist Tomogr, 1989 ,13: 240-243 . |
| 11. | Hanada N, Namai S, Kobayashi C, et al. Case report of pulmonary epithelioid hemangioendothelioma ( in Japanese ) . Nihon Kokyuki Gakkai Zasshi, 2003, 41: 144-149. |
| 12. | Roudier-Pujol C, Enjolras O, Lacronique J, et al. Multifocal epithelioid hemangioendothelioma with partial remission after interferon alpha-2a treatment( in French) . Ann Dermatol Venerol,1994, 121: 898-904. |
| 13. | Bagan P, Hassan M, Le Pimpec Barthes F, et al. Prognostic factors and surgical indications of pulmonary epithelioid hemangioendothelioma: a review of the literature. Ann Thorac Surg, 2006, 82: 2010-2013. |
| 14. | Kitaichi M, Nagai S, Nishimura K, et al. Pulmonary epithelioid hemangioendothelioma in 21 patients, including three with partial spontaneous regression. Eur Respir J, 1998, 12: 89-96. |
- 1. Dail DH, Liebow AA, Gmelich JT, et al, Intravascular, bronchiolar,and alveolar tumor of the lung( IVBAT) . An analysis of twenty cases of a peculiar sclerosing endothelial tumor. Cancer, 1983, 51 : 452 -464.
- 2. Amin RM, Hiroshima K, Kokubo T, et al. Risk factors and independent predictors of survival in patients with pulmonary epithelioid hemangioendothelioma. Review of the literature and a case report. Respirology, 2006, 11: 818 -815.
- 3. 葉甫登, 張峰. 肺上皮樣血管內(nèi)皮瘤( 附1 例報告及文獻(xiàn)復(fù)習(xí)) .臨床肺科雜志, 2007, 12: 332-334 .
- 4. Weiss SW, Ishak KG, Dail DH, et al. Epithelioid hemangioendothelioma and related lesions. Semin Diagn Pathol,1986, 3: 259 -287.
- 5. Schattenberg T, Kam R, Klopp M, et al. Pulmonary epithelioid hemangioendothelioma: report of three cases. Surg Today, 2008, 38 :844-849.
- 6. Bharadwaj R, Hejmadi R, Desai S. Pericardial effusion and raised CA-125 level-unusual manifestations of primary pulmonary epithelioid hemangioendothelioma. Indian J Cancer, 1999, 36: 194 -197.
- 7. Travis WD, Brambilla E, Mueller-Hermelink HK, et al. Pathology and genetics of tumours of the lung, pleure, thymus and heart. WHO classification of tumours. Lyon: IARC Press; 2004 .
- 8. Fagen K, Silverman ED, Cole RL. et al. Detection of a pulmonary epithelioid hemangioendothelioma by FDG PET Scan. Clin NuclMed, 2004, 29: 758-759 .
- 9. Cronin P, Arenberg D. Pulmonary epithelioid hemangioendothelioma:an unusual case and a review of the literature. Chest, 2004, 125:789-793.
- 10. Ross GJ, Violi L, Friedman AC, et al. Intravascular bronchioloalveolar tumor: CT and pathologic correlation. J Comp Assist Tomogr, 1989 ,13: 240-243 .
- 11. Hanada N, Namai S, Kobayashi C, et al. Case report of pulmonary epithelioid hemangioendothelioma ( in Japanese ) . Nihon Kokyuki Gakkai Zasshi, 2003, 41: 144-149.
- 12. Roudier-Pujol C, Enjolras O, Lacronique J, et al. Multifocal epithelioid hemangioendothelioma with partial remission after interferon alpha-2a treatment( in French) . Ann Dermatol Venerol,1994, 121: 898-904.
- 13. Bagan P, Hassan M, Le Pimpec Barthes F, et al. Prognostic factors and surgical indications of pulmonary epithelioid hemangioendothelioma: a review of the literature. Ann Thorac Surg, 2006, 82: 2010-2013.
- 14. Kitaichi M, Nagai S, Nishimura K, et al. Pulmonary epithelioid hemangioendothelioma in 21 patients, including three with partial spontaneous regression. Eur Respir J, 1998, 12: 89-96.