• 首都醫(yī)科大學(xué)附屬北京安貞醫(yī)院呼吸內(nèi)科(北京 100029);

目的 探討少見病因所致肺動脈高壓的診斷和治療。方法 回顧性分析2001 年2 月~2008 年3 月北京安貞醫(yī)院診治的4 例少見病因所致肺動脈高壓患者的臨床、實(shí)驗(yàn)室檢查、診斷及治療。結(jié)果 原發(fā)性膽汁性肝硬化、甲狀腺功能亢進(jìn)癥、抗磷脂綜合征、肺動脈肉瘤等均可引起肺動脈高壓, 給予相應(yīng)治療后病情有不同程度緩解。結(jié)論 一些少見病因可致肺動脈高壓, 提高這方面的認(rèn)識有助于早期診治, 改善患者預(yù)后。

引用本文: 高元明,張向峰,劉雙. 少見病因所致肺動脈高壓的診斷和治療. 中國呼吸與危重監(jiān)護(hù)雜志, 2009, 09(1): 68-71. doi: 復(fù)制

1. 黃燕, 李為民. 結(jié)締組織病與肺動脈高壓研究進(jìn)展. 中國呼吸與危重監(jiān)護(hù)雜志, 2007, 6: 473-475.
2. Mantz FA, Craig E. Portal axis thrombosis with spontaneous portacaval shunt and resultant cor pulmonale. Arch Pathol Lab Med, 1951 ,52: 91-97.
3. Yohida EM, Erb SR, Ostrow DN, et al. Pulmonary hypertension associated with primary biliary cirrhosis in the absence of portal hypertension:a case report. Gut, 1994, 35: 280-282.
4. 沈敏, 張桓, 張奉春. 原發(fā)性膽汁性肝硬化合并肺動脈高壓的臨床分析. 中華醫(yī)學(xué)雜志, 2005, 85: 946-948.
5. Nakchbandi IA, Wirth JA, Inzucchi SE. Pulmonary hypertension caused by Graves’thyrotoxicosis: normal pulmonary hemodynamics restored by 131I treatment. Chest, 1999, 116: 1483-1485.
6. Benjaminov FS, Prentice M, Sniderman KW, et al. Portpulmonanry hypertension in decompensated cirrhosis with refractory ascites. Gut,2003, 52: 1355-1362.
7. Budhiraja R, Hassoun PM. Portpulmonary hypertension: a tale of two circulation. Chest, 2003, 123: 562-572.
8. Ronald C. Thyrotoxicosis as a risk factor for pulmonary arterial hypertension. Ann Intern Med, 2006, 144: 222.
9. 吳紅花, 郭曉燕, 高燕明. 甲狀腺功能亢進(jìn)性心臟病75 例臨床分析. 中華醫(yī)學(xué)雜志, 2007, 87: 262-264.
10. Marvisi M, Brianti M, Marani G, et al. Hyperthyroidismand pulmonary hypertension. Respir Med, 2002, 96: 215-220.
11. Yazar A, Doven O, Atis S, et al. Systolic pulmonary artery pressure and serum uric acid levels in patients with hyperthyroidism. Arch Med Res, 2003, 34: 35-40.
12. 單淵東, 曾學(xué)軍, 黃曉明, 主編. 內(nèi)科疑難病診斷— 協(xié)和醫(yī)生臨床思維例釋. 北京: 中國協(xié)和醫(yī)科大學(xué)出版社, 2007, 265-271.
13. 熊長明, 程顯聲, 柳志紅, 等. 肺動脈肉瘤誤診為肺血栓栓塞癥三例原因分析. 中華結(jié)核和呼吸雜志, 2004, 27: 737-739.
14. Kim JH, Gutierrez FR, Lee EY, et al. Primary leiomyosarcoma of the pulmonary artery: a diagnostic dilemma. Clin Imaging,2003,27: 206-211.
15. Parish JM, Rosenow ES, Swensen SJ, et al. Pulmonary artery sarcoma:clinical features. Chest, 1996, 110: 1480-1488.
  1. 1. 黃燕, 李為民. 結(jié)締組織病與肺動脈高壓研究進(jìn)展. 中國呼吸與危重監(jiān)護(hù)雜志, 2007, 6: 473-475.
  2. 2. Mantz FA, Craig E. Portal axis thrombosis with spontaneous portacaval shunt and resultant cor pulmonale. Arch Pathol Lab Med, 1951 ,52: 91-97.
  3. 3. Yohida EM, Erb SR, Ostrow DN, et al. Pulmonary hypertension associated with primary biliary cirrhosis in the absence of portal hypertension:a case report. Gut, 1994, 35: 280-282.
  4. 4. 沈敏, 張桓, 張奉春. 原發(fā)性膽汁性肝硬化合并肺動脈高壓的臨床分析. 中華醫(yī)學(xué)雜志, 2005, 85: 946-948.
  5. 5. Nakchbandi IA, Wirth JA, Inzucchi SE. Pulmonary hypertension caused by Graves’thyrotoxicosis: normal pulmonary hemodynamics restored by 131I treatment. Chest, 1999, 116: 1483-1485.
  6. 6. Benjaminov FS, Prentice M, Sniderman KW, et al. Portpulmonanry hypertension in decompensated cirrhosis with refractory ascites. Gut,2003, 52: 1355-1362.
  7. 7. Budhiraja R, Hassoun PM. Portpulmonary hypertension: a tale of two circulation. Chest, 2003, 123: 562-572.
  8. 8. Ronald C. Thyrotoxicosis as a risk factor for pulmonary arterial hypertension. Ann Intern Med, 2006, 144: 222.
  9. 9. 吳紅花, 郭曉燕, 高燕明. 甲狀腺功能亢進(jìn)性心臟病75 例臨床分析. 中華醫(yī)學(xué)雜志, 2007, 87: 262-264.
  10. 10. Marvisi M, Brianti M, Marani G, et al. Hyperthyroidismand pulmonary hypertension. Respir Med, 2002, 96: 215-220.
  11. 11. Yazar A, Doven O, Atis S, et al. Systolic pulmonary artery pressure and serum uric acid levels in patients with hyperthyroidism. Arch Med Res, 2003, 34: 35-40.
  12. 12. 單淵東, 曾學(xué)軍, 黃曉明, 主編. 內(nèi)科疑難病診斷— 協(xié)和醫(yī)生臨床思維例釋. 北京: 中國協(xié)和醫(yī)科大學(xué)出版社, 2007, 265-271.
  13. 13. 熊長明, 程顯聲, 柳志紅, 等. 肺動脈肉瘤誤診為肺血栓栓塞癥三例原因分析. 中華結(jié)核和呼吸雜志, 2004, 27: 737-739.
  14. 14. Kim JH, Gutierrez FR, Lee EY, et al. Primary leiomyosarcoma of the pulmonary artery: a diagnostic dilemma. Clin Imaging,2003,27: 206-211.
  15. 15. Parish JM, Rosenow ES, Swensen SJ, et al. Pulmonary artery sarcoma:clinical features. Chest, 1996, 110: 1480-1488.
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