目的 探討使用雙水平氣道正壓通氣(BiPAP)無創(chuàng)呼吸機對需長期輔助機械通氣的患者進(jìn)行有創(chuàng)機械通氣的可行性。方法 選擇2004年6月~2007年11月,因呼吸衰竭入住呼吸ICU,經(jīng)面罩機械通氣等方法撤機失敗或不能進(jìn)行面罩機械通氣的11例患者,給予氣管切開,更換BiPAP無創(chuàng)呼吸機行有創(chuàng)機械通氣,觀察改用無創(chuàng)呼吸機前后動脈血氣、住院時間、出院(或達(dá)到出院標(biāo)準(zhǔn))后存活時間等指標(biāo)。結(jié)果 無創(chuàng)通氣吸氣壓力設(shè)定為16~26 cm H2O,平均21.3 cm H2O,呼氣壓力4 cm H2O,呼吸頻率16次/min?;颊叩钠骄≡海ɑ蜻_(dá)到出院標(biāo)準(zhǔn))時間為(91.5±50.2)d,改為BiPAP呼吸機后平均住院(或達(dá)到出院標(biāo)準(zhǔn))時間為(23.5±12.2)d。出院(或達(dá)到出院標(biāo)準(zhǔn))后平均存活時間為(353.1±296.5)d,截至隨訪結(jié)束(2008年1月13日)有4例患者仍存活。BiPAP呼吸機使用前后動脈血pH、PaCO2、PaO2及SaO2均無顯著差異(P均 gt;0.05)。結(jié)論 對于臨床穩(wěn)定、仍需長期機械通氣的呼吸衰竭患者,使用BiPAP無創(chuàng)呼吸機通過氣管切開行有創(chuàng)機械通氣是可選擇的方法。
引用本文: 馬壯,史亮,槐永軍,謝華,林育紅,劉蕾. 雙水平氣道正壓通氣無創(chuàng)呼吸機進(jìn)行有創(chuàng)機械通氣的臨床研究. 中國呼吸與危重監(jiān)護(hù)雜志, 2008, 08(3): 187-189. doi: 復(fù)制
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