• 首都醫(yī)科大學附屬北京朝陽醫(yī)院北京呼吸疾病研究所(北京100020);

高頻通氣(HFV)是一種高通氣頻率和低潮氣量的通氣方式,其通氣頻率至少為機體正常呼吸頻率的4倍,而潮氣量近于或小于解剖死腔。其主要類型包括:高頻正壓通氣、高頻噴射通氣和高頻振蕩通氣等。其中,高頻振蕩通氣(HFOV)是目前公認的最先進高頻通氣技術(shù),在臨床中應用最廣泛。

引用本文: 夏金根,詹慶元,孫兵. 高頻振蕩通氣在成人呼吸衰竭患者中的應用. 中國呼吸與危重監(jiān)護雜志, 2008, 08(1): 65-68. doi: 復制

1. Johnson AH,Peacock JL,Greenough A,et al.High-frequency oscillatory ventilation for the prevention of chronic lung disease of prematurity.N Engl J Med,2002,347:633-642.
2. Courtney SE,Durand DJ,Asselin JM,et al.High-frequency oscillatory ventilation versus conventional mechanical ventilation for very-low-birth-weight infants.N Engl J Med,2002,347:643-652.
3. Plavka R,Kopecký P,Sebron V,et al.A prospective randomized comparison of conventional mechanical ventilation and very early high frequency oscillatory ventilation in extremely premature newborns with respiratory distress syndrome.Intensive Care Med,1999,25:68-75.
4. Gerstmann DR,Minton SD,Stoddard RA,et al.The Provo multicenter early high-frequency oscillatory ventilation trial:improved pulmonary and clinical outcome in respiratory distress syndrome.Pediatrics,1996,98:1044-1057.
5. Arnold JH,Anas NG,Luckett P,et al.High-frequency oscillatory ventilation in pediatric respiratory failure:a multicenter experience.Crit Care Med,2000,28:3913-3919.
6. Chan KP,Stewart TE,Mehta S.High-frequency oscillatory ventilation for adult patients with ARDS.Chest,2007,131:1907-1916.
7. Slutsky AS,Tremblay LN.Multiple system organ failure.Is mechanical ventilation a contributing factor? Am J Respir Crit Care Med,1998,157:1721-1725.
8. Vincent JL,Zambon M.Why do patients who have acute lung injury/acute respiratory distress syndrome die from multiple organ dysfunction syndrome? Implications for management?Clin Chest Med,2006,27:725-731.
9. Imai Y,Slutsky AS.High-frequency oscillatory ventilation and ventilator-induced lung injury.Crit Care Med,2005,33:S129-S134.
10. 尹輝明,蔣玉蘭,米允仕,等.高頻震蕩通氣和持續(xù)氣道正壓開放肺的比較.中國呼吸與危重監(jiān)護雜志,2006,5:428-431.
11. Imai Y,Nakagawa S,Ito Y,et al.Comparison of lung protection strategies using conventional and high-frequency oscillatory ventilation.J Appl Physiol,2001,91:1836-1844.
12. Fort P,F(xiàn)armer C,Westerman J,et al.High-frequency oscillatory ventilation for adult respiratory distress syndrome--a pilot study.Crit Care Med,1997,25:937-947.
13. Claridge JA,Hostetter RG,Lowson SM,et al.High-frequency oscillatory ventilation can be effective as rescue therapy for refractory acute lung dysfunction.Am Surg,1999,65:1092-1096.
14. Mehta S,Lapinsky SE,Hallett DC,et al.Prospective trial of high-frequency oscillation in adults with acute respiratory distress syndrome.Crit Care Med,2001,29:1360-1369.
15. Cartotto R,Cooper AB,Esmond JR,et al.Early clinical experience with high-frequency oscillatory ventilation for ARDS in adult burn patients.J Burn Care Rehabil,2001,22:325-333.
16. Andersen FA,Guttormsen AB,F(xiàn)laatten HK.High frequency oscillatory ventilation in adult patients with acute respiratory distress syndrome--a retrospective study.Acta Anaesthesiol Scand,2002,46:1082-1088.
17. David M,Weiler N,Heinrichs W,et al.High-frequency oscillatory ventilation in adult acute respiratory distress syndrome.Intensive Care Med,2003,29:1656-1665.
18. Cartotto R,Ellis S,Gomez M,et al.High frequency oscillatory ventilation in burn patients with the acute respiratory distress syndrome.Burns,2004,30:453-463.
19. Mehta S,Granton J,MacDonald RJ,et al.High-frequency oscillatory ventilation in adults:the Toronto experience.Chest,2004,126:518-527.
20. Kao KC,Tsai YH,Wu YK,et al.High frequency oscillatory ventilation for surgical patients with acute respiratory distress syndrome.J Trauma,2006,61:837-843.
21. Finkielman JD,Gajic O,F(xiàn)armer JC,et al.The initial Mayo Clinic experience using high-frequency oscillatory ventilation for adult patients:a retrospective study.BMC Emerg Med,2006,6:2.
22. Derdak S,Mehta S,Stewart TE,et al.High-frequency oscillatory ventilation for acute respiratory distress syndrome in adults:a randomized,controlled trial.Am J Respir Crit Care Med,2002,166:801-808.
23. Bollen CW,van Well GT,Sherry T,et al.High frequency oscillatory ventilation compared with conventional mechanical ventilation in adult respiratory distress syndrome:a randomized controlled trial.Crit Care,2005,9:R430-439.
24. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome.The Acute Respiratory Distress Syndrome Network.N Engl J Med,2000,342:1301-1308.
25. Varkul MD,Stewart TE,Lapinsky SE,et al.Successful use of combined high-frequency oscillatory ventilation,inhaled nitric oxide,and prone positioning in the acute respiratory distress syndrome.Anesthesiology,2001,95:797-799.
26. Mehta S,MacDonald R,Hallett DC,et al.Acute oxygenation response to inhaled nitric oxide when combined with high-frequency oscillatory ventilation in adults with acute respiratory distress syndrome.Crit Care Med,2003,31:383-389.
27. Demory D,Michelet P,Arnal JM,et al.High-frequency oscillatory ventilation following prone positioning prevents a further impairment in oxygenation.Crit Care Med,2007,35:106-111.
28. Ferguson ND,Chiche JD,Kacmarek RM,et al.Combining high-frequency oscillatory ventilation and recruitment maneuvers in adults with early acute respiratory distress syndrome:the Treatment with Oscillation and an Open Lung Strategy (TOOLS) Trial pilot study.Crit Care Med,2005,33:479-486.
29. Arroliga A,F(xiàn)rutos-Vivar F,Hall J,et al.Use of sedatives and neuromuscular blockers in a cohort of patients receiving mechanical ventilation.Chest,2005,128:496-506.
30. Putensen C,Muders T,Varelmann D,et al.The impact of spontaneous breathing during mechanical ventilation.Curr Opin Crit Care,2006,12:13-18.
31. van Heerde M,Roubik K,Kopelent V,et al Unloading work of breathing during high-frequency oscillatory ventilation:a bench study.Crit Care,2006,10:R103.
  1. 1. Johnson AH,Peacock JL,Greenough A,et al.High-frequency oscillatory ventilation for the prevention of chronic lung disease of prematurity.N Engl J Med,2002,347:633-642.
  2. 2. Courtney SE,Durand DJ,Asselin JM,et al.High-frequency oscillatory ventilation versus conventional mechanical ventilation for very-low-birth-weight infants.N Engl J Med,2002,347:643-652.
  3. 3. Plavka R,Kopecký P,Sebron V,et al.A prospective randomized comparison of conventional mechanical ventilation and very early high frequency oscillatory ventilation in extremely premature newborns with respiratory distress syndrome.Intensive Care Med,1999,25:68-75.
  4. 4. Gerstmann DR,Minton SD,Stoddard RA,et al.The Provo multicenter early high-frequency oscillatory ventilation trial:improved pulmonary and clinical outcome in respiratory distress syndrome.Pediatrics,1996,98:1044-1057.
  5. 5. Arnold JH,Anas NG,Luckett P,et al.High-frequency oscillatory ventilation in pediatric respiratory failure:a multicenter experience.Crit Care Med,2000,28:3913-3919.
  6. 6. Chan KP,Stewart TE,Mehta S.High-frequency oscillatory ventilation for adult patients with ARDS.Chest,2007,131:1907-1916.
  7. 7. Slutsky AS,Tremblay LN.Multiple system organ failure.Is mechanical ventilation a contributing factor? Am J Respir Crit Care Med,1998,157:1721-1725.
  8. 8. Vincent JL,Zambon M.Why do patients who have acute lung injury/acute respiratory distress syndrome die from multiple organ dysfunction syndrome? Implications for management?Clin Chest Med,2006,27:725-731.
  9. 9. Imai Y,Slutsky AS.High-frequency oscillatory ventilation and ventilator-induced lung injury.Crit Care Med,2005,33:S129-S134.
  10. 10. 尹輝明,蔣玉蘭,米允仕,等.高頻震蕩通氣和持續(xù)氣道正壓開放肺的比較.中國呼吸與危重監(jiān)護雜志,2006,5:428-431.
  11. 11. Imai Y,Nakagawa S,Ito Y,et al.Comparison of lung protection strategies using conventional and high-frequency oscillatory ventilation.J Appl Physiol,2001,91:1836-1844.
  12. 12. Fort P,F(xiàn)armer C,Westerman J,et al.High-frequency oscillatory ventilation for adult respiratory distress syndrome--a pilot study.Crit Care Med,1997,25:937-947.
  13. 13. Claridge JA,Hostetter RG,Lowson SM,et al.High-frequency oscillatory ventilation can be effective as rescue therapy for refractory acute lung dysfunction.Am Surg,1999,65:1092-1096.
  14. 14. Mehta S,Lapinsky SE,Hallett DC,et al.Prospective trial of high-frequency oscillation in adults with acute respiratory distress syndrome.Crit Care Med,2001,29:1360-1369.
  15. 15. Cartotto R,Cooper AB,Esmond JR,et al.Early clinical experience with high-frequency oscillatory ventilation for ARDS in adult burn patients.J Burn Care Rehabil,2001,22:325-333.
  16. 16. Andersen FA,Guttormsen AB,F(xiàn)laatten HK.High frequency oscillatory ventilation in adult patients with acute respiratory distress syndrome--a retrospective study.Acta Anaesthesiol Scand,2002,46:1082-1088.
  17. 17. David M,Weiler N,Heinrichs W,et al.High-frequency oscillatory ventilation in adult acute respiratory distress syndrome.Intensive Care Med,2003,29:1656-1665.
  18. 18. Cartotto R,Ellis S,Gomez M,et al.High frequency oscillatory ventilation in burn patients with the acute respiratory distress syndrome.Burns,2004,30:453-463.
  19. 19. Mehta S,Granton J,MacDonald RJ,et al.High-frequency oscillatory ventilation in adults:the Toronto experience.Chest,2004,126:518-527.
  20. 20. Kao KC,Tsai YH,Wu YK,et al.High frequency oscillatory ventilation for surgical patients with acute respiratory distress syndrome.J Trauma,2006,61:837-843.
  21. 21. Finkielman JD,Gajic O,F(xiàn)armer JC,et al.The initial Mayo Clinic experience using high-frequency oscillatory ventilation for adult patients:a retrospective study.BMC Emerg Med,2006,6:2.
  22. 22. Derdak S,Mehta S,Stewart TE,et al.High-frequency oscillatory ventilation for acute respiratory distress syndrome in adults:a randomized,controlled trial.Am J Respir Crit Care Med,2002,166:801-808.
  23. 23. Bollen CW,van Well GT,Sherry T,et al.High frequency oscillatory ventilation compared with conventional mechanical ventilation in adult respiratory distress syndrome:a randomized controlled trial.Crit Care,2005,9:R430-439.
  24. 24. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome.The Acute Respiratory Distress Syndrome Network.N Engl J Med,2000,342:1301-1308.
  25. 25. Varkul MD,Stewart TE,Lapinsky SE,et al.Successful use of combined high-frequency oscillatory ventilation,inhaled nitric oxide,and prone positioning in the acute respiratory distress syndrome.Anesthesiology,2001,95:797-799.
  26. 26. Mehta S,MacDonald R,Hallett DC,et al.Acute oxygenation response to inhaled nitric oxide when combined with high-frequency oscillatory ventilation in adults with acute respiratory distress syndrome.Crit Care Med,2003,31:383-389.
  27. 27. Demory D,Michelet P,Arnal JM,et al.High-frequency oscillatory ventilation following prone positioning prevents a further impairment in oxygenation.Crit Care Med,2007,35:106-111.
  28. 28. Ferguson ND,Chiche JD,Kacmarek RM,et al.Combining high-frequency oscillatory ventilation and recruitment maneuvers in adults with early acute respiratory distress syndrome:the Treatment with Oscillation and an Open Lung Strategy (TOOLS) Trial pilot study.Crit Care Med,2005,33:479-486.
  29. 29. Arroliga A,F(xiàn)rutos-Vivar F,Hall J,et al.Use of sedatives and neuromuscular blockers in a cohort of patients receiving mechanical ventilation.Chest,2005,128:496-506.
  30. 30. Putensen C,Muders T,Varelmann D,et al.The impact of spontaneous breathing during mechanical ventilation.Curr Opin Crit Care,2006,12:13-18.
  31. 31. van Heerde M,Roubik K,Kopelent V,et al Unloading work of breathing during high-frequency oscillatory ventilation:a bench study.Crit Care,2006,10:R103.
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