• 首都醫(yī)科大學附屬北京朝陽醫(yī)院北京呼吸疾病研究所(北京100020);

高頻通氣(HFV)是一種高通氣頻率和低潮氣量的通氣方式，其通氣頻率至少為機體正常呼吸頻率的4倍，而潮氣量近于或小于解剖死腔。其主要類型包括：高頻正壓通氣、高頻噴射通氣和高頻振蕩通氣等。其中，高頻振蕩通氣(HFOV)是目前公認的最先進高頻通氣技術(shù)，在臨床中應用最廣泛。

引用本文： 夏金根,詹慶元,孫兵. 高頻振蕩通氣在成人呼吸衰竭患者中的應用. 中國呼吸與危重監(jiān)護雜志, 2008, 08(1): 65-68. doi: 復制

1. Johnson AH，Peacock JL，Greenough A，et al.High-frequency oscillatory ventilation for the prevention of chronic lung disease of prematurity.N Engl J Med，2002，347：633-642.
2. Courtney SE，Durand DJ，Asselin JM，et al.High-frequency oscillatory ventilation versus conventional mechanical ventilation for very-low-birth-weight infants.N Engl J Med，2002，347：643-652.
3. Plavka R，Kopecký P，Sebron V，et al.A prospective randomized comparison of conventional mechanical ventilation and very early high frequency oscillatory ventilation in extremely premature newborns with respiratory distress syndrome.Intensive Care Med，1999，25：68-75.
4. Gerstmann DR，Minton SD，Stoddard RA，et al.The Provo multicenter early high-frequency oscillatory ventilation trial：improved pulmonary and clinical outcome in respiratory distress syndrome.Pediatrics，1996，98：1044-1057.
5. Arnold JH，Anas NG，Luckett P，et al.High-frequency oscillatory ventilation in pediatric respiratory failure：a multicenter experience.Crit Care Med，2000，28：3913-3919.
6. Chan KP，Stewart TE，Mehta S.High-frequency oscillatory ventilation for adult patients with ARDS.Chest，2007，131：1907-1916.
7. Slutsky AS，Tremblay LN.Multiple system organ failure.Is mechanical ventilation a contributing factor? Am J Respir Crit Care Med，1998，157：1721-1725.
8. Vincent JL，Zambon M.Why do patients who have acute lung injury/acute respiratory distress syndrome die from multiple organ dysfunction syndrome? Implications for management?Clin Chest Med，2006，27：725-731.
9. Imai Y，Slutsky AS.High-frequency oscillatory ventilation and ventilator-induced lung injury.Crit Care Med，2005，33：S129-S134.
10. 尹輝明，蔣玉蘭，米允仕，等.高頻震蕩通氣和持續(xù)氣道正壓開放肺的比較.中國呼吸與危重監(jiān)護雜志，2006，5：428-431.
11. Imai Y，Nakagawa S，Ito Y，et al.Comparison of lung protection strategies using conventional and high-frequency oscillatory ventilation.J Appl Physiol，2001，91：1836-1844.
12. Fort P，F(xiàn)armer C，Westerman J，et al.High-frequency oscillatory ventilation for adult respiratory distress syndrome--a pilot study.Crit Care Med，1997，25：937-947.
13. Claridge JA，Hostetter RG，Lowson SM，et al.High-frequency oscillatory ventilation can be effective as rescue therapy for refractory acute lung dysfunction.Am Surg，1999，65：1092-1096.
14. Mehta S，Lapinsky SE，Hallett DC，et al.Prospective trial of high-frequency oscillation in adults with acute respiratory distress syndrome.Crit Care Med，2001，29：1360-1369.
15. Cartotto R，Cooper AB，Esmond JR，et al.Early clinical experience with high-frequency oscillatory ventilation for ARDS in adult burn patients.J Burn Care Rehabil，2001，22：325-333.
16. Andersen FA，Guttormsen AB，F(xiàn)laatten HK.High frequency oscillatory ventilation in adult patients with acute respiratory distress syndrome--a retrospective study.Acta Anaesthesiol Scand，2002，46：1082-1088.
17. David M，Weiler N，Heinrichs W，et al.High-frequency oscillatory ventilation in adult acute respiratory distress syndrome.Intensive Care Med，2003，29：1656-1665.
18. Cartotto R，Ellis S，Gomez M，et al.High frequency oscillatory ventilation in burn patients with the acute respiratory distress syndrome.Burns，2004，30：453-463.
19. Mehta S，Granton J，MacDonald RJ，et al.High-frequency oscillatory ventilation in adults：the Toronto experience.Chest，2004，126：518-527.
20. Kao KC，Tsai YH，Wu YK，et al.High frequency oscillatory ventilation for surgical patients with acute respiratory distress syndrome.J Trauma，2006，61：837-843.
21. Finkielman JD，Gajic O，F(xiàn)armer JC，et al.The initial Mayo Clinic experience using high-frequency oscillatory ventilation for adult patients：a retrospective study.BMC Emerg Med，2006，6：2.
22. Derdak S，Mehta S，Stewart TE，et al.High-frequency oscillatory ventilation for acute respiratory distress syndrome in adults：a randomized，controlled trial.Am J Respir Crit Care Med，2002，166：801-808.
23. Bollen CW，van Well GT，Sherry T，et al.High frequency oscillatory ventilation compared with conventional mechanical ventilation in adult respiratory distress syndrome：a randomized controlled trial.Crit Care，2005，9：R430-439.
24. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome.The Acute Respiratory Distress Syndrome Network.N Engl J Med，2000，342：1301-1308.
25. Varkul MD，Stewart TE，Lapinsky SE，et al.Successful use of combined high-frequency oscillatory ventilation，inhaled nitric oxide，and prone positioning in the acute respiratory distress syndrome.Anesthesiology，2001，95：797-799.
26. Mehta S，MacDonald R，Hallett DC，et al.Acute oxygenation response to inhaled nitric oxide when combined with high-frequency oscillatory ventilation in adults with acute respiratory distress syndrome.Crit Care Med，2003，31：383-389.
27. Demory D，Michelet P，Arnal JM，et al.High-frequency oscillatory ventilation following prone positioning prevents a further impairment in oxygenation.Crit Care Med，2007，35：106-111.
28. Ferguson ND，Chiche JD，Kacmarek RM，et al.Combining high-frequency oscillatory ventilation and recruitment maneuvers in adults with early acute respiratory distress syndrome：the Treatment with Oscillation and an Open Lung Strategy (TOOLS) Trial pilot study.Crit Care Med，2005，33：479-486.
29. Arroliga A，F(xiàn)rutos-Vivar F，Hall J，et al.Use of sedatives and neuromuscular blockers in a cohort of patients receiving mechanical ventilation.Chest，2005，128：496-506.
30. Putensen C，Muders T，Varelmann D，et al.The impact of spontaneous breathing during mechanical ventilation.Curr Opin Crit Care，2006，12：13-18.
31. van Heerde M，Roubik K，Kopelent V，et al Unloading work of breathing during high-frequency oscillatory ventilation：a bench study.Crit Care，2006，10：R103.
  1. 1. Johnson AH，Peacock JL，Greenough A，et al.High-frequency oscillatory ventilation for the prevention of chronic lung disease of prematurity.N Engl J Med，2002，347：633-642.
  2. 2. Courtney SE，Durand DJ，Asselin JM，et al.High-frequency oscillatory ventilation versus conventional mechanical ventilation for very-low-birth-weight infants.N Engl J Med，2002，347：643-652.
  3. 3. Plavka R，Kopecký P，Sebron V，et al.A prospective randomized comparison of conventional mechanical ventilation and very early high frequency oscillatory ventilation in extremely premature newborns with respiratory distress syndrome.Intensive Care Med，1999，25：68-75.
  4. 4. Gerstmann DR，Minton SD，Stoddard RA，et al.The Provo multicenter early high-frequency oscillatory ventilation trial：improved pulmonary and clinical outcome in respiratory distress syndrome.Pediatrics，1996，98：1044-1057.
  5. 5. Arnold JH，Anas NG，Luckett P，et al.High-frequency oscillatory ventilation in pediatric respiratory failure：a multicenter experience.Crit Care Med，2000，28：3913-3919.
  6. 6. Chan KP，Stewart TE，Mehta S.High-frequency oscillatory ventilation for adult patients with ARDS.Chest，2007，131：1907-1916.
  7. 7. Slutsky AS，Tremblay LN.Multiple system organ failure.Is mechanical ventilation a contributing factor? Am J Respir Crit Care Med，1998，157：1721-1725.
  8. 8. Vincent JL，Zambon M.Why do patients who have acute lung injury/acute respiratory distress syndrome die from multiple organ dysfunction syndrome? Implications for management?Clin Chest Med，2006，27：725-731.
  9. 9. Imai Y，Slutsky AS.High-frequency oscillatory ventilation and ventilator-induced lung injury.Crit Care Med，2005，33：S129-S134.
  10. 10. 尹輝明，蔣玉蘭，米允仕，等.高頻震蕩通氣和持續(xù)氣道正壓開放肺的比較.中國呼吸與危重監(jiān)護雜志，2006，5：428-431.
  11. 11. Imai Y，Nakagawa S，Ito Y，et al.Comparison of lung protection strategies using conventional and high-frequency oscillatory ventilation.J Appl Physiol，2001，91：1836-1844.
  12. 12. Fort P，F(xiàn)armer C，Westerman J，et al.High-frequency oscillatory ventilation for adult respiratory distress syndrome--a pilot study.Crit Care Med，1997，25：937-947.
  13. 13. Claridge JA，Hostetter RG，Lowson SM，et al.High-frequency oscillatory ventilation can be effective as rescue therapy for refractory acute lung dysfunction.Am Surg，1999，65：1092-1096.
  14. 14. Mehta S，Lapinsky SE，Hallett DC，et al.Prospective trial of high-frequency oscillation in adults with acute respiratory distress syndrome.Crit Care Med，2001，29：1360-1369.
  15. 15. Cartotto R，Cooper AB，Esmond JR，et al.Early clinical experience with high-frequency oscillatory ventilation for ARDS in adult burn patients.J Burn Care Rehabil，2001，22：325-333.
  16. 16. Andersen FA，Guttormsen AB，F(xiàn)laatten HK.High frequency oscillatory ventilation in adult patients with acute respiratory distress syndrome--a retrospective study.Acta Anaesthesiol Scand，2002，46：1082-1088.
  17. 17. David M，Weiler N，Heinrichs W，et al.High-frequency oscillatory ventilation in adult acute respiratory distress syndrome.Intensive Care Med，2003，29：1656-1665.
  18. 18. Cartotto R，Ellis S，Gomez M，et al.High frequency oscillatory ventilation in burn patients with the acute respiratory distress syndrome.Burns，2004，30：453-463.
  19. 19. Mehta S，Granton J，MacDonald RJ，et al.High-frequency oscillatory ventilation in adults：the Toronto experience.Chest，2004，126：518-527.
  20. 20. Kao KC，Tsai YH，Wu YK，et al.High frequency oscillatory ventilation for surgical patients with acute respiratory distress syndrome.J Trauma，2006，61：837-843.
  21. 21. Finkielman JD，Gajic O，F(xiàn)armer JC，et al.The initial Mayo Clinic experience using high-frequency oscillatory ventilation for adult patients：a retrospective study.BMC Emerg Med，2006，6：2.
  22. 22. Derdak S，Mehta S，Stewart TE，et al.High-frequency oscillatory ventilation for acute respiratory distress syndrome in adults：a randomized，controlled trial.Am J Respir Crit Care Med，2002，166：801-808.
  23. 23. Bollen CW，van Well GT，Sherry T，et al.High frequency oscillatory ventilation compared with conventional mechanical ventilation in adult respiratory distress syndrome：a randomized controlled trial.Crit Care，2005，9：R430-439.
  24. 24. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome.The Acute Respiratory Distress Syndrome Network.N Engl J Med，2000，342：1301-1308.
  25. 25. Varkul MD，Stewart TE，Lapinsky SE，et al.Successful use of combined high-frequency oscillatory ventilation，inhaled nitric oxide，and prone positioning in the acute respiratory distress syndrome.Anesthesiology，2001，95：797-799.
  26. 26. Mehta S，MacDonald R，Hallett DC，et al.Acute oxygenation response to inhaled nitric oxide when combined with high-frequency oscillatory ventilation in adults with acute respiratory distress syndrome.Crit Care Med，2003，31：383-389.
  27. 27. Demory D，Michelet P，Arnal JM，et al.High-frequency oscillatory ventilation following prone positioning prevents a further impairment in oxygenation.Crit Care Med，2007，35：106-111.
  28. 28. Ferguson ND，Chiche JD，Kacmarek RM，et al.Combining high-frequency oscillatory ventilation and recruitment maneuvers in adults with early acute respiratory distress syndrome：the Treatment with Oscillation and an Open Lung Strategy (TOOLS) Trial pilot study.Crit Care Med，2005，33：479-486.
  29. 29. Arroliga A，F(xiàn)rutos-Vivar F，Hall J，et al.Use of sedatives and neuromuscular blockers in a cohort of patients receiving mechanical ventilation.Chest，2005，128：496-506.
  30. 30. Putensen C，Muders T，Varelmann D，et al.The impact of spontaneous breathing during mechanical ventilation.Curr Opin Crit Care，2006，12：13-18.
  31. 31. van Heerde M，Roubik K，Kopelent V，et al Unloading work of breathing during high-frequency oscillatory ventilation：a bench study.Crit Care，2006，10：R103.

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