肺泡蛋白沉積癥（PAP）是一種罕見的呼吸系統(tǒng)疾病，主要是由于肺泡腔中大量的嗜酸性富含脂質(zhì)和蛋白質(zhì)的物質(zhì)沉積[1]，可分為先天性、繼發(fā)性和獲得性三類。目前PAP最有效的治療是全肺灌洗[2]。多數(shù)文獻報道的是對初次診斷的PAP患者的全肺灌洗治療。2005年我們收治了1例PAP患者，經(jīng)全肺灌洗治療10個月后復(fù)診，根據(jù)其影像學(xué)表現(xiàn)再次進行全肺灌洗治療，現(xiàn)報告如下。
引用本文： 朱際平,鄭玲,于力克. 再次全肺灌洗治療肺泡蛋白沉積癥一例. 中國呼吸與危重監(jiān)護雜志, 2007, 6(1): 68-69. doi: 復(fù)制
| 1. | Trapnell BC, Whitsett JA, Nakata K. Pulmonary alveolar proteinosis. N Engl J Med,2003，349:2527-2539. |
| 2. | Beccaria M, Luisetti M, Rodi G,et al. Long-term durable benefit after whole lung lavage in pulmonary alveolar proteinosis.Eur Respir J,2004，23: 526-531. |
| 3. | Ramirez J, Schultz RB, Dutton RE. Pulmonary alveolar proteinosis: a new technique and rationale for treatment. Arch Intern Med,1963，112:419-431. |
| 4. | Goldstein LS, Kavuru MS, Curtis-McCarthy P, et al. Pulmonary alveolar proteinosis: clinical features and outcomes. Chest, 1998，114: 1357-1362. |
| 5. | Richard A.Morris Manual of Clinical problems in pulmonary medicine 5th ed .天津：天津科技翻譯出版公司,2003.524. |
| 6. | 蔡后榮，崔蘇陽，金陵，等.體外循環(huán)膜氧合支持下全肺灌洗治療肺泡蛋白沉積癥一例并文獻復(fù)習(xí).中華結(jié)核和呼吸雜志，2005，28：242-244. |
| 7. | Simpson RI, Ramsay MA, Millard MW, et al. Management of pulmonary alveolar proteinosis by repeated bronchoalveolar lavage. Proc (Bayl Univ Med Cent),2000，13:119-120. |
| 8. | Seymour JF, Presneill JJ.Pulmonary alveolar proteinosis:progress in the first 44 years. Am J Respir Crit Care Med, 2002，166:215-235. |
- 1. Trapnell BC, Whitsett JA, Nakata K. Pulmonary alveolar proteinosis. N Engl J Med,2003，349:2527-2539.
- 2. Beccaria M, Luisetti M, Rodi G,et al. Long-term durable benefit after whole lung lavage in pulmonary alveolar proteinosis.Eur Respir J,2004，23: 526-531.
- 3. Ramirez J, Schultz RB, Dutton RE. Pulmonary alveolar proteinosis: a new technique and rationale for treatment. Arch Intern Med,1963，112:419-431.
- 4. Goldstein LS, Kavuru MS, Curtis-McCarthy P, et al. Pulmonary alveolar proteinosis: clinical features and outcomes. Chest, 1998，114: 1357-1362.
- 5. Richard A.Morris Manual of Clinical problems in pulmonary medicine 5th ed .天津：天津科技翻譯出版公司,2003.524.
- 6. 蔡后榮，崔蘇陽，金陵，等.體外循環(huán)膜氧合支持下全肺灌洗治療肺泡蛋白沉積癥一例并文獻復(fù)習(xí).中華結(jié)核和呼吸雜志，2005，28：242-244.
- 7. Simpson RI, Ramsay MA, Millard MW, et al. Management of pulmonary alveolar proteinosis by repeated bronchoalveolar lavage. Proc (Bayl Univ Med Cent),2000，13:119-120.
- 8. Seymour JF, Presneill JJ.Pulmonary alveolar proteinosis:progress in the first 44 years. Am J Respir Crit Care Med, 2002，166:215-235.