采用酶偶聯(lián)比色法測定47例(103例次)阻塞性黃疸(阻黃)和53例(83例次)無黃疸單純膽囊結(jié)石患者血清總膽酸(TCA)的水平,并探討其與黃疸程度及肝細(xì)胞損害的關(guān)系。結(jié)果表明:阻黃組TCA明顯高于無黃疸組(P<0.001),與血清總膽紅素、直接膽紅素、谷丙轉(zhuǎn)氨酶均有正相關(guān)關(guān)系。說明TCA水平不僅與黃疸程度有關(guān),而且與肝細(xì)胞受損狀況有關(guān)。單項(xiàng)檢測TCA對阻黃診斷的敏感性和特異性分別為69.9%。和71.1%,與單項(xiàng)檢測堿性磷酸酶的敏感性(79.6%)和特異性(69.9%)相近。聯(lián)合檢測二者并不能提高對阻黃診斷的特異性(56.6%)。
引用本文: 梁廷波,鄭樹森,盛建明,楊榮偉. 梗阻性黃疸患者血清總膽酸測定的臨床意義. 中國普外基礎(chǔ)與臨床雜志, 1996, 3(2): 88-89. doi: 復(fù)制
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