對阻塞性黃疸模型鼠的心臟、肝臟和腎臟的形態(tài)學改變及其與膽汁酸血癥的關系進行了研究，結(jié)果表名，膽道梗阻1~2周，心臟、肝臟和腎臟的形態(tài)學改變及其與膽汁酸血癥的關系進行了研究。結(jié)果表明，膽道梗阻1~2周，心臟、肝臟和腎臟細胞均有線粒體等超微結(jié)構改變；管飼膽酸鈉使血清膽汁酸峰濃度接近膽管結(jié)扎2周組的平均濃度時，上述臟器的細胞超微結(jié)構損害相似。提示膽汁酸滯留是造成阻塞性黃疸全身性損害的因素之一。
引用本文： 牟一平 ,彭淑牖. 阻塞性黃疸鼠臟器損害與膽汁酸血癥的關系. 中國普外基礎與臨床雜志, 1997, 4(2): 78-80. doi: 復制
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- 3. Scott-Conner CH,Grogan JB.The Pathophysiology of biliary obstruction and its effection on phagocytic and immune function.J Surg Res,1994;57:316.
- 4. Green J,Beyer R,Sideman S,et al.The "jaundiced heart":a possible explanation for postoperative shock in obstructive jaundice.Surgery,1986;100(1):14.
- 5. Shibayama Y.Factors producing bile infrction and bile duct proliferation in biliary obstruction.J Pathol,1990;160(1):57.