治療犬未控制出血的失血性休克,采用高滲鹽水(實(shí)驗(yàn)組)和輸血+生理鹽水(對(duì)照組)輸注的兩種不同方法,并比較兩組損傷血管(犬尾動(dòng)靜脈)出血量。結(jié)果表明:實(shí)驗(yàn)組和對(duì)照組比較,休克期尾動(dòng)靜脈出血量分別為35.2ml和34.6ml,無顯著性差異(P>0.05);實(shí)驗(yàn)組復(fù)蘇早期及后期出血量分別為15.10±1.52ml和14.00±1.37ml,對(duì)照組分別為14.20±1.52ml和12.90±1.71ml,亦無顯著性差異(P>0.05),但均較休克期出血量明顯減少(P<0.05)。本實(shí)驗(yàn)結(jié)果提示:未控制出血的失血性休克應(yīng)用高滲鹽水復(fù)蘇,未促使損傷血管繼續(xù)出血,且安全有效。臨床觀察也證實(shí)此點(diǎn)。
引用本文: 蔡秀軍,牟一平,彭淑牖. 高滲鹽水治療未控制出血的失血性休克動(dòng)物實(shí)驗(yàn)及臨床觀察. 中國普外基礎(chǔ)與臨床雜志, 1998, 5(1): 14-15. doi: 復(fù)制
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- 2. Traverso LW, Bellamy RF, Hollenbach SJ,et al.Hypertonic NaCl∶effect on hemodynamics and survival after hemorrhage in swine. J Trauma, 1987; 27(1)∶32.
- 3. 蔡秀軍,彭淑牖,江觀玉等. 7.5%高滲氯化鈉溶液治療失血性休克20例報(bào)告. 實(shí)用外科雜志,1992;12(12)∶646.
- 4. 蔡秀軍.高滲氯化鈉溶液治療失血性休克的動(dòng)物實(shí)驗(yàn)研究.浙江醫(yī)科大學(xué)博士論文集,1993.
- 5. Gross D, Landau EH, Klin B, et al. Quantitative measurement of bleeding following hypertonic saline therapy in uncontrolled hemorrhage shock. J Trauma,1989; 29(1)∶79.
- 6. Vassar MJ, Perry CA, Holcroft JW, et al.Analysis of potential risks associated with 7.5% sodium chloride resuscitation of traumatic shock. Arch Surg, 1990; 125(10)∶1309.