目的 探討肝移植治療終末期肝病的臨床療效。 方法 回顧分析原位肝移植7例及親體部分肝移植(LRLT)4例的臨床資料,其中肝炎肝硬變5例,肝豆?fàn)詈俗冃?例。對乙肝肝硬變者采用拉米呋啶加小劑量抗HBV-Ig治療。 結(jié)果 10例康復(fù)出院,1例死于MODS。4例LRLT全部存活。術(shù)后并發(fā)癥: 腹腔出血2例,ARDS 3例; 4例乙型肝炎肝硬變者術(shù)后HBV-DNA(-)。6例肝豆?fàn)詈俗冃?,術(shù)后銅氧化酶均正常。結(jié)論 肝移植是終末期肝病的有效治療手段,活體供肝是解決我國供肝來源問題又一方向,外科技術(shù)是減少圍手術(shù)期并發(fā)癥的關(guān)鍵。
引用本文: 王學(xué)浩,李相成,張峰,錢建民,孔連寶,張浩. 臨床肝移植11例報道. 中國普外基礎(chǔ)與臨床雜志, 2001, 8(5): 310-312. doi: 復(fù)制
1. | Belle SH,Detre KM.Report from PittsburghUNOS liver transplantation regitry 〔J〕. Transplant Proc,1993; 25(1pt2)∶1137. |
2. | Seehofer D,Rayes N,Neuhaus R,et al.Antiviral combination therapy for lamivudineresistant hepatitis B reinfection after liver transplantation 〔J〕.Transpl Int,2000; 34(1)∶126. |
3. | Teo EK,Han SH,Terrault N,et al.Related articles liver transplantation in patients with hepatitis B virus infection: outcome in asian versus white patients 〔J〕.Hepatology, 2001; 34(1)∶126. |
4. | Fan ST,Cheung ST,Lo CM.Related articles indications for liver transplantation in patients with chronic hepatitis B and C virus infection and hepatocellular carcinoma 〔J〕.Gastroenterol Hepatol,2000; 15(Suppl)∶E181. |
5. | Bismuch H,Chiche L,Adan R,et al. Surgical treatment of Hepatocellular carcinoma in cirrhosis: liver resection or transplantation 〔J〕.Transplantation Pros,1993; 25(1pt2)∶1066. |
6. | Busuttil RW,Seu P,Millis PJM,et al.Liver transplantation in children 〔J〕.Ann Surg,1991; 213(1)∶48. |
7. | Broelsch CE,Whitington PF,Emond JC,et al.Liver transplantation in children from living related donors.Surgical techniques and results 〔J〕.Ann Surg,1991; 214(4)∶428. |
8. | 王學(xué)浩,杜競輝,張峰等.供體供肝原位部分肝移植一例報告 〔J〕.中華器官移植雜志,1995; 16(3)∶133. |
9. | 王學(xué)浩,張峰,李相成等.親體部分肝移植二例報道 〔J〕.中華肝膽外科雜志,2001; 7(4)∶封二. |
10. | Kubota K,Makuuchi M,Takayama T,et al.Successful hepatic vein reconstruction in 42 consecutive living related liver transplantations 〔J〕.Surgery,2000; 128(1)∶48. |
11. | Inomofo T, Nishszawa F,Sasaki H,et al.Experience of 120 microsurgical reconstruction of hepatic artery in living related liver transplantation 〔J〕.Surgery,1996; 119(1)∶20. |
12. | Pastacaldi S,Teixeira R,Montalto P, et al.Hepatic artery thrombosis after orthotopic liver transplantation:a review of nonsurgical causes 〔J〕.Liver Transpl, 2001; 7(2)∶75. |
- 1. Belle SH,Detre KM.Report from PittsburghUNOS liver transplantation regitry 〔J〕. Transplant Proc,1993; 25(1pt2)∶1137.
- 2. Seehofer D,Rayes N,Neuhaus R,et al.Antiviral combination therapy for lamivudineresistant hepatitis B reinfection after liver transplantation 〔J〕.Transpl Int,2000; 34(1)∶126.
- 3. Teo EK,Han SH,Terrault N,et al.Related articles liver transplantation in patients with hepatitis B virus infection: outcome in asian versus white patients 〔J〕.Hepatology, 2001; 34(1)∶126.
- 4. Fan ST,Cheung ST,Lo CM.Related articles indications for liver transplantation in patients with chronic hepatitis B and C virus infection and hepatocellular carcinoma 〔J〕.Gastroenterol Hepatol,2000; 15(Suppl)∶E181.
- 5. Bismuch H,Chiche L,Adan R,et al. Surgical treatment of Hepatocellular carcinoma in cirrhosis: liver resection or transplantation 〔J〕.Transplantation Pros,1993; 25(1pt2)∶1066.
- 6. Busuttil RW,Seu P,Millis PJM,et al.Liver transplantation in children 〔J〕.Ann Surg,1991; 213(1)∶48.
- 7. Broelsch CE,Whitington PF,Emond JC,et al.Liver transplantation in children from living related donors.Surgical techniques and results 〔J〕.Ann Surg,1991; 214(4)∶428.
- 8. 王學(xué)浩,杜競輝,張峰等.供體供肝原位部分肝移植一例報告 〔J〕.中華器官移植雜志,1995; 16(3)∶133.
- 9. 王學(xué)浩,張峰,李相成等.親體部分肝移植二例報道 〔J〕.中華肝膽外科雜志,2001; 7(4)∶封二.
- 10. Kubota K,Makuuchi M,Takayama T,et al.Successful hepatic vein reconstruction in 42 consecutive living related liver transplantations 〔J〕.Surgery,2000; 128(1)∶48.
- 11. Inomofo T, Nishszawa F,Sasaki H,et al.Experience of 120 microsurgical reconstruction of hepatic artery in living related liver transplantation 〔J〕.Surgery,1996; 119(1)∶20.
- 12. Pastacaldi S,Teixeira R,Montalto P, et al.Hepatic artery thrombosis after orthotopic liver transplantation:a review of nonsurgical causes 〔J〕.Liver Transpl, 2001; 7(2)∶75.