目的研究兔股靜脈延遲移植血漿內(nèi)皮素(ET)和一氧化氮(NO)含量的變化及其與血管痙攣、靜脈移植的關(guān)系。方法用放射免疫方法測(cè)定局部血漿ET的含量，用硝酸還原酶法及紫外可見分光光度計(jì)測(cè)定局部血漿中NO-2/NO-3含量，間接反映NO水平。結(jié)果游離股靜脈(FV)局部血漿ET含量術(shù)后2 h和4 h明顯增高(P＜0.01)，術(shù)后8 h也增高(P＜0.05)； 局部血漿NO含量術(shù)后2 h和4 h下降非常顯著(P＜0.01)，術(shù)后24 h則又顯著增高(P＜0.05)。結(jié)論游離(未切斷)FV術(shù)后16～24 h，延遲切斷準(zhǔn)備移植的FV血漿中ET含量恢復(fù)正常，NO含量明顯增高，是移植靜脈血管危象發(fā)生率下降的原因，此時(shí)為切斷靜脈進(jìn)行移植的最佳時(shí)間。
引用本文： 王李華,鄭樹森,余耀生,潘松齡,申桂娟,張鴻坤. 兔股靜脈延遲移植內(nèi)皮素和一氧化氮變化的意義. 中國(guó)普外基礎(chǔ)與臨床雜志, 2002, 9(4): 235-237. doi: 復(fù)制
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