• 華中科技大學(xué)同濟醫(yī)學(xué)院附屬協(xié)和醫(yī)院（武漢430022）;

引用本文： 陳道達(dá),鄭海. 胃癌的基因治療現(xiàn)狀、問題和展望. 中國普外基礎(chǔ)與臨床雜志, 2002, 9(3): 141-142. doi: 復(fù)制

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1. 參考文獻(xiàn).
2. Tanaka T,Kanai F,Lan KH, et al. Adenovirusmediated gene therapy of gastric carcinoma using cancerspecific gene expression in vivo [J]. Biochem Res Commun， 1997; 231∶775.
3. Hart S,Knight A,Harbottle R, et al. Cell binding and internalization by filamentous phage displaying a cyclic ArgGlyAspcontaining peptide [J]. J Biologi Chemis, 1994; 269∶12468.
4. Steele RJC, Thompson AM,Hall P, et al. The p53 tumor suppressor gene [J]. Br J Surg, 1988; 85∶1460.
5. Ohashi M, Kanai F. Adenovirus mediated p53 tumor suppressor gene therapy for human gastric cancer cells in vitro and in vivo [J].Gut, 1999; 44∶366.
6. Bouvet M, Ellis LM. Adenovirusmediated wildtype p53 gene transfer downregulates vascular endothelial growth factor expression and inhibits angeiogenesis in human colon cancer [J]. Cancer Res, 1998; 58∶2288.
7. Lowe S, Ruley H. p53dependent apoptosis modulstes the cytotoxicity of anticancer agents [J]. Cell， 1993; 362∶847.
8. Nakano H, Namatame K, Suzuki T, et al. The evaluation of proliferating activity in gastric carcinoma stained by proliferating cell nuclear antigen (PCNA) [J]. Nippon Geka Gakkai Zasshi, 1992; 93(2)∶216.
9. Sakakura C, Hagiwara A. The antiproliferative effect of proliferating cell nuclear antigenspecific antisense oligonucleotides on human gastric cancer cell lines [J]. Surg Today, 1995; 25∶184.
10. Yoshida K, Kawami H. Retovirally transmitted gene therapy for gastric carcinoma using herps simplex virus thymidine kinase gene [J]. Cancer, 1995; 75∶1467.
11. Inaba M, Swada H. Circumvention of 5fluorouracil resistance in human stomach cancer cells by uracil phosphoribosyltransferase gene transduction [J]. Jap J Cancer Research, 1999; 90∶349.
12. Freema SM, Abboud CN. The "bystander effect": tumour regression when a fraction to be tumour mass is geneticlly modified [J]. Cancer Research， 1993; 53∶5274.
13. Tanaka F,Abe M. The antihuman tumour effect and generation of human cytotoxic T cells in SCID mice given human periperal blood lymphocytes by the in vivo transfer of the IL6 gene using adenovirus vector [J]. Cancer Research, 1997; 57∶1335.
14. Tagawa M, Goto S. Reduced tumorigenicity of human gastric carcinoma cells engeered to produce IL2 in SCID mice reconstituted with periperal blood cells from cancer patients [J]. Cancer Letters, 1998; 123∶517.
  1. 1. 參考文獻(xiàn).
  2. 2. Tanaka T,Kanai F,Lan KH, et al. Adenovirusmediated gene therapy of gastric carcinoma using cancerspecific gene expression in vivo [J]. Biochem Res Commun， 1997; 231∶775.
  3. 3. Hart S,Knight A,Harbottle R, et al. Cell binding and internalization by filamentous phage displaying a cyclic ArgGlyAspcontaining peptide [J]. J Biologi Chemis, 1994; 269∶12468.
  4. 4. Steele RJC, Thompson AM,Hall P, et al. The p53 tumor suppressor gene [J]. Br J Surg, 1988; 85∶1460.
  5. 5. Ohashi M, Kanai F. Adenovirus mediated p53 tumor suppressor gene therapy for human gastric cancer cells in vitro and in vivo [J].Gut, 1999; 44∶366.
  6. 6. Bouvet M, Ellis LM. Adenovirusmediated wildtype p53 gene transfer downregulates vascular endothelial growth factor expression and inhibits angeiogenesis in human colon cancer [J]. Cancer Res, 1998; 58∶2288.
  7. 7. Lowe S, Ruley H. p53dependent apoptosis modulstes the cytotoxicity of anticancer agents [J]. Cell， 1993; 362∶847.
  8. 8. Nakano H, Namatame K, Suzuki T, et al. The evaluation of proliferating activity in gastric carcinoma stained by proliferating cell nuclear antigen (PCNA) [J]. Nippon Geka Gakkai Zasshi, 1992; 93(2)∶216.
  9. 9. Sakakura C, Hagiwara A. The antiproliferative effect of proliferating cell nuclear antigenspecific antisense oligonucleotides on human gastric cancer cell lines [J]. Surg Today, 1995; 25∶184.
  10. 10. Yoshida K, Kawami H. Retovirally transmitted gene therapy for gastric carcinoma using herps simplex virus thymidine kinase gene [J]. Cancer, 1995; 75∶1467.
  11. 11. Inaba M, Swada H. Circumvention of 5fluorouracil resistance in human stomach cancer cells by uracil phosphoribosyltransferase gene transduction [J]. Jap J Cancer Research, 1999; 90∶349.
  12. 12. Freema SM, Abboud CN. The "bystander effect": tumour regression when a fraction to be tumour mass is geneticlly modified [J]. Cancer Research， 1993; 53∶5274.
  13. 13. Tanaka F,Abe M. The antihuman tumour effect and generation of human cytotoxic T cells in SCID mice given human periperal blood lymphocytes by the in vivo transfer of the IL6 gene using adenovirus vector [J]. Cancer Research, 1997; 57∶1335.
  14. 14. Tagawa M, Goto S. Reduced tumorigenicity of human gastric carcinoma cells engeered to produce IL2 in SCID mice reconstituted with periperal blood cells from cancer patients [J]. Cancer Letters, 1998; 123∶517.