目的 探討胰腺脂肪替代（fatty replacement of pancreas）的CT表現(xiàn)及臨床意義。方法 收集CT發(fā)現(xiàn)胰腺脂肪替代患者3例的資料。CT掃描包括平掃、動(dòng)脈期及門(mén)靜脈期,觀察胰腺各部的形態(tài)、大小、密度、胰腺小葉及小葉間隔、胰管走行的顯示情況，確定脂肪替代的部位，并結(jié)合臨床資料及實(shí)驗(yàn)室檢查結(jié)果分析其臨床意義。結(jié)果 ①CT表現(xiàn)： 完全性脂肪替代2例（胰頭前后分、頸、體、尾），大部分脂肪替代1例（胰頭前分、頸、體）； 2例胰腺形態(tài)均規(guī)整，1例欠規(guī)整； 2例胰腺體積稍大，1例胰腺體積正常； 3例小葉間隔均增寬及胰腺小葉均萎縮； 3例主胰管及分支均無(wú)狹窄梗阻。②臨床情況： 3例患者均有慢性腹瀉，2例合并糖尿?。ㄆ渲?例還合并膽總管炎伴慢性梗阻），另1例合并膽總管小結(jié)石，3例血清脂肪酶及1例血清淀粉酶降低。結(jié)論 胰腺脂肪替代的CT表現(xiàn)有一定的特征性，常合并有胰腺內(nèi)、外分泌功能不足的臨床表現(xiàn)。
引用本文： 李迎春,宋彬,徐雋,楊洋,印隆林. 胰腺脂肪替代的CT表現(xiàn)及臨床意義（附3例報(bào)告）. 中國(guó)普外基礎(chǔ)與臨床雜志, 2006, 13(6): 724-728. doi: 復(fù)制
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- 2. 武忠弼， 楊光華主編. 中華外科病理學(xué) [M]. 上卷. 第1版. 北京： 人民衛(wèi)生出版社， 2002∶ 942～943.
- 3. Soyer P, Spelle L, Pelage JP, et al. Cystic fibrosis in adolescents and adults: fatty replacement of the pancreas——CT evaluation and functional correlation [J]. Radiology， 1999; 210(3)∶611.
- 4. Willi UV, Reddish JM, Teele RL. Cystic fibrosis: its characteristic appearance on abdominal sonography [J]. AJR Am J Roentgenol， 1980; 134(5)∶ 1005.
- 5. Tham RT, Heyerman HG, Falke TH, et al. Cystic fibrosis: MR imaging of the pancreas [J]. Radiology， 1991; 179(1)∶ 183.
- 6. Daneman A, Gaskin K, Martin DJ, et al. Pancreatic changes in cystic fibrosis: CT and sonographic appearances [J]. AJR Am J Roentgenol， 1983; 141(4)∶ 653.
- 7. Heuck A, Maubach PA, Reiser M, et al. Age-related morphology of the normal pancreas on computed tomography [J]. Gastrointest Radiol， 1987; 12(1)∶ 18.
- 8. Patel S, Bellon EM, Haaga J, et al. Fat replacement of the exocrine pancreas [J]. AJR Am J Roentgenol， 1980; 135(4)∶ 843.
- 9. Matsumoto S, Mori H, Miyake H, et al. Uneven fatty replacement of the pancreas: evaluation with CT [J]. Radiology， 1995; 194(2)∶ 453.
- 10. Li Y, Cao L, Wang BZ, et al. The structural change of pancreatic tissue of fatty rats induced with high-fat food and its pathological significance [J]. Chin J Histochem Cytochem, 2004； 13(3)∶ 353.
- 11. Katz DS, Nardi PM, Hines J, et al. Lipomas of the pancreas [J]. AJR Am J Roentgenol, 1998; 170(6)∶1485.