目的 評(píng)價(jià)影像學(xué)技術(shù)在肝脂肪變性的定性及定量診斷中的價(jià)值. 方法 對(duì)比超聲、CT及MRI對(duì)肝脂肪變性的定性及定量診斷的臨床應(yīng)用現(xiàn)況,總結(jié)它們各自的進(jìn)展情況及其優(yōu)、缺點(diǎn). 結(jié)果 超聲可對(duì)肝脂肪變性的定性及定量診斷進(jìn)行初步的篩選和估計(jì),CT對(duì)肝脂肪變性的定量診斷更為可靠,MRI則具有更高的靈敏度和特異性. 結(jié)論 影像學(xué)在肝脂肪變性的定性及定量診斷中具有重要的臨床價(jià)值,特別是MRI波譜成像及雙梯度回波成像可對(duì)肝脂肪變性作出準(zhǔn)確的定量診斷.
引用本文： 趙黎明,陽(yáng)寧?kù)o,宋彬. 脂肪肝影像學(xué)評(píng)價(jià)的研究進(jìn)展. 中國(guó)普外基礎(chǔ)與臨床雜志, 2008, 15(1): 68-70. doi: 復(fù)制
| 1. | <>[1]范建高,曾民德.脂肪肝的研究進(jìn)展[J].胃腸病學(xué)和肝病學(xué)雜志,1999; 8(2)∶149. |
| 2. | 周永昌,郭萬學(xué)主編.超聲醫(yī)學(xué)[M].第3版.北京:科學(xué)技術(shù)文獻(xiàn)出版社,1992∶598. |
| 3. | 陳偉明,楊益虎,吳意.超聲量化診斷均勻性脂肪肝的初步研究[J].中華實(shí)用中西醫(yī)雜志,2005; 18(21)∶1453. |
| 4. | 盛明洪,呂斌,周興祥,等.二維超聲圖像定量診斷脂肪肝病變程度的應(yīng)用研究[J].臨床超聲醫(yī)學(xué)雜志,2005; 7(1)∶18. |
| 5. | 陳蘇寧,陸雯,胡小濤,等.用超聲研究脂肪肝的血流動(dòng)力學(xué)變化[J].上海醫(yī)學(xué)影像,2005; 14(1)∶47. |
| 6. | Graif M,Yanuka M,Baraz M,et al.Quantitative estimation of attenuation in ultrasound video images:correlation with histology in diffuse liver disease[J].Invest Radiol,2000; 35(5)∶319. |
| 7. | 李漢英,袁莉芳,董常峰,等.超聲組織定征對(duì)均勻性脂肪肝分度的測(cè)量研究[J].中國(guó)超聲診斷雜志,2005; 6(4)∶261. |
| 8. | 劉云霞,王潔貞,劉建平,等.脂肪肝影像學(xué)診斷性試驗(yàn)的系統(tǒng)評(píng)價(jià)[J].中國(guó)醫(yī)學(xué)科學(xué)院學(xué)報(bào),2004; 26(5)∶580. |
| 9. | 李果珍,戴建平,王儀生,等主編.臨床CT診斷學(xué)[M].第2版.北京:中國(guó)科學(xué)技術(shù)出版社,1994∶437. |
| 10. | 許驊,王蒿,耿道穎,等.CT定量分析脂肪肝的臨床應(yīng)用探討[J].中國(guó)醫(yī)學(xué)計(jì)算機(jī)成像雜志,2004; 10(4)∶250. |
| 11. | 賀文,錢林學(xué),趙繼學(xué),等.CT定量診斷脂肪肝的臨床研究[J].中華放射學(xué)雜志,2001; 35(11)∶829. |
| 12. | 徐蕓,王振豫,宋燕,等.CT圖像的面罩式覆蓋法對(duì)脂肪肝脂肪浸潤(rùn)的定量分析及臨床意義[J].中華消化雜志,2000; 20(6)∶422. |
| 13. | 劉軍,高鑫,陳剛,等.CT定量評(píng)價(jià)脂肪肝[J].上海醫(yī)學(xué)影像雜志,2002; 11(3)∶170. |
| 14. | Ricci C,Longo R,Gioulis E,et al.Noninvasive in vivo quantitative assessment of fat content in human liver[J].J Hepatol,1997; 27(1)∶108. |
| 15. | 李文政,彭光春,湯恢煥,等.脂肪肝CT、MRI定量診斷的對(duì)照實(shí)驗(yàn)研究[J].醫(yī)學(xué)影像學(xué)雜志,2005; 15(4)∶294. |
| 16. | Qayyum A,Goh JS,Kakar S,et al.Accuracy of liver fat quantification at MR imaging:comparison of out-of-phase gradient-echo and fat-saturated fast spin-echo techniques--initial experience[J].Radiology,2005; 237(2)∶507. |
| 17. | Rinella ME,McCarthy R,Thakrar K,et al.Dual-echo,chemical shift gradient-echo magnetic resonance imaging to quantifyhepatic steatosis:implications for living liver donation[J].Liver Transpl,2003; 9(8)∶851. |
| 18. | Machann J,Thamer C,Schnoedt B,et al.Hepatic lipid accumulation in healthy subjects:a comparative study using spectral fat-selective MRI and volume-localized 1H-MR spectroscopy[J].Magn Reson Med,2006; 55(4)∶913. |
| 19. | 范明霞,田建明,陸建平,等.活體1H磁共振波譜分析在大鼠脂肪肝中應(yīng)用價(jià)值的初步研究[J].中國(guó)影像技術(shù),2004; 20(10)∶1503. |
| 20. | Soher BJ,Vermathen P,Schuff N,et al.Short TE in vivo 1H-MR spectroscopic imaging at 1.5 T:acquisition and automated spectral analysis[J].Magn Reson Imaging,2000; 18(9)∶1159. |
| 21. | Pollesello P,Masutti F,Crocè LS,et al.1H-NMR spectroscopic studies of lipid extracts from human fatty liver[J].Biochem Biophys Res Commun,1993; 192(3)∶1217. |
| 22. | Thomas EL,Hamilton G,Patel N,et al.Hepatic triglyceride content and its relation to body adiposity:a magnetic resonance imaging and proton magnetic resonance spectroscopy study[J].Gut,2005; 54(1)∶122. |
- 1. <>[1]范建高,曾民德.脂肪肝的研究進(jìn)展[J].胃腸病學(xué)和肝病學(xué)雜志,1999; 8(2)∶149.
- 2. 周永昌,郭萬學(xué)主編.超聲醫(yī)學(xué)[M].第3版.北京:科學(xué)技術(shù)文獻(xiàn)出版社,1992∶598.
- 3. 陳偉明,楊益虎,吳意.超聲量化診斷均勻性脂肪肝的初步研究[J].中華實(shí)用中西醫(yī)雜志,2005; 18(21)∶1453.
- 4. 盛明洪,呂斌,周興祥,等.二維超聲圖像定量診斷脂肪肝病變程度的應(yīng)用研究[J].臨床超聲醫(yī)學(xué)雜志,2005; 7(1)∶18.
- 5. 陳蘇寧,陸雯,胡小濤,等.用超聲研究脂肪肝的血流動(dòng)力學(xué)變化[J].上海醫(yī)學(xué)影像,2005; 14(1)∶47.
- 6. Graif M,Yanuka M,Baraz M,et al.Quantitative estimation of attenuation in ultrasound video images:correlation with histology in diffuse liver disease[J].Invest Radiol,2000; 35(5)∶319.
- 7. 李漢英,袁莉芳,董常峰,等.超聲組織定征對(duì)均勻性脂肪肝分度的測(cè)量研究[J].中國(guó)超聲診斷雜志,2005; 6(4)∶261.
- 8. 劉云霞,王潔貞,劉建平,等.脂肪肝影像學(xué)診斷性試驗(yàn)的系統(tǒng)評(píng)價(jià)[J].中國(guó)醫(yī)學(xué)科學(xué)院學(xué)報(bào),2004; 26(5)∶580.
- 9. 李果珍,戴建平,王儀生,等主編.臨床CT診斷學(xué)[M].第2版.北京:中國(guó)科學(xué)技術(shù)出版社,1994∶437.
- 10. 許驊,王蒿,耿道穎,等.CT定量分析脂肪肝的臨床應(yīng)用探討[J].中國(guó)醫(yī)學(xué)計(jì)算機(jī)成像雜志,2004; 10(4)∶250.
- 11. 賀文,錢林學(xué),趙繼學(xué),等.CT定量診斷脂肪肝的臨床研究[J].中華放射學(xué)雜志,2001; 35(11)∶829.
- 12. 徐蕓,王振豫,宋燕,等.CT圖像的面罩式覆蓋法對(duì)脂肪肝脂肪浸潤(rùn)的定量分析及臨床意義[J].中華消化雜志,2000; 20(6)∶422.
- 13. 劉軍,高鑫,陳剛,等.CT定量評(píng)價(jià)脂肪肝[J].上海醫(yī)學(xué)影像雜志,2002; 11(3)∶170.
- 14. Ricci C,Longo R,Gioulis E,et al.Noninvasive in vivo quantitative assessment of fat content in human liver[J].J Hepatol,1997; 27(1)∶108.
- 15. 李文政,彭光春,湯恢煥,等.脂肪肝CT、MRI定量診斷的對(duì)照實(shí)驗(yàn)研究[J].醫(yī)學(xué)影像學(xué)雜志,2005; 15(4)∶294.
- 16. Qayyum A,Goh JS,Kakar S,et al.Accuracy of liver fat quantification at MR imaging:comparison of out-of-phase gradient-echo and fat-saturated fast spin-echo techniques--initial experience[J].Radiology,2005; 237(2)∶507.
- 17. Rinella ME,McCarthy R,Thakrar K,et al.Dual-echo,chemical shift gradient-echo magnetic resonance imaging to quantifyhepatic steatosis:implications for living liver donation[J].Liver Transpl,2003; 9(8)∶851.
- 18. Machann J,Thamer C,Schnoedt B,et al.Hepatic lipid accumulation in healthy subjects:a comparative study using spectral fat-selective MRI and volume-localized 1H-MR spectroscopy[J].Magn Reson Med,2006; 55(4)∶913.
- 19. 范明霞,田建明,陸建平,等.活體1H磁共振波譜分析在大鼠脂肪肝中應(yīng)用價(jià)值的初步研究[J].中國(guó)影像技術(shù),2004; 20(10)∶1503.
- 20. Soher BJ,Vermathen P,Schuff N,et al.Short TE in vivo 1H-MR spectroscopic imaging at 1.5 T:acquisition and automated spectral analysis[J].Magn Reson Imaging,2000; 18(9)∶1159.
- 21. Pollesello P,Masutti F,Crocè LS,et al.1H-NMR spectroscopic studies of lipid extracts from human fatty liver[J].Biochem Biophys Res Commun,1993; 192(3)∶1217.
- 22. Thomas EL,Hamilton G,Patel N,et al.Hepatic triglyceride content and its relation to body adiposity:a magnetic resonance imaging and proton magnetic resonance spectroscopy study[J].Gut,2005; 54(1)∶122.